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Description

Hypoxia stabilizes HIF-1, which binds to the hypoxia response element (HRE) of the GPX4 promoter to inhibit GPX4 transcription (176)

Price BR, Sudduth TL, Weekman EM, Johnson S, Hawthorne D, Woolums A, Wilcock DM (2020) Therapeutic Trem2 activation ameliorates amyloid-beta deposition and improves cognition in the 5XFAD model of amyloid deposition

10.1111/andr.12444 96

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